As mentioned earlier, members of the genus plasmodium are digenetic. As such, they complete their life cycle in two hosts. In P. vivax, the definitive hosts are Anopheles mosquitoes (also known as the vector), while humans are the intermediate asexual hosts. From the bloodstream, the sporozoites reach the liver through gliding motility. This life stage is known as sporozoite. P. vivax starts the infection cycle through an infected mosquito sending saliva into an injection wound while extracting blood to stop coagulation of the blood, sending sporozoites from the mosquito's salivary glands into the bloodstream. 2. they complete their life cycle in two hosts: 1. Secondary host or intermediate host: human is the secondary host. This cycle consists of both sexual and asexual cycles that occur in the vector/mosquito and vertebrate respectively. Life cycle of Plasmodium vivax. Its life cycle is completed both by asexual and sexual phases. The life cycle of Plasmodium vivax is digenetic involving two hosts as mentioned earlier. Primary host or definitive host: Female Anopheles mosquito is the primary host. Like all malaria parasites, P. vivax has a complex life cycle. It infects a definitive insect host, where sexual reproduction occurs, and an intermediate vertebrate host, where asexual amplification occurs. 1) Gametocytes – Stage 1 – The male gametocytes called microgametocytes and female gametocytes called microgametocytes are transmitted through an anopheles mosquito during a blood meal. Life cycle of Plasmodium vivax is digenetic i.e. Plasmodium parasites have an elaborate life-cyle with multiple stages: Infective stage, when the parasite enters the vertebrate host with a vector bite. The organism which contains sexual phase of the parasite and is regarded as definitive host. Life Cycle of Plasmodium: Plasmodium parasites have a complex life cycle that includes three stages namely Gametocytes, Sporozoites and Merozoites. During its life cycle, P. vivax assumes many different physical forms. Exoerythrocytic stage, in which the sporozoite undergoes multiple rounds of asexual divisions (merogony or schizongony) and matures into merozoites.

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